Cutaneous Amyloid Elastosis Revealing Multiple Myeloma with Systemic Amyloidosis

Cutaneous amyloid elastosis revealing multiple myeloma with systemic amyloidosis.

Multiple Myeloma with HBs Antigenemia Presented with Hoarseness and Systemic Amyloidosis

Primary systemic amyloidosis associated with multiple myeloma.

This case report is about a 48-year-old female patient with systemic amyloidosis and multiple myeloma simultaneously. Amyloid cutaneous infiltrative lesions like papules, nodules, or plaques with a serous-hemorrhagic aspect were found in the eyelids, neck and retroauricular region, among others. She had presented intermittent papular lesions on the upper eyelids one year before, which worsened ...

Myeloma-associated Systemic Amyloidosis with an Extensive Cutaneous Involvement

Primary systemic amyloidosis (PSA) mostly occurs in the setting of plasma cell dyscrasias.[1] It is difficult to diagnose as it usually presents with nonspecific symptoms.[2] Mucocutaneous manifestations occur in 29%–40% of cases and provide important diagnostic clues.[3] We report an atypical case where an unusually extensive cutaneous involvement provided the first sign of a widespread multio...

Primary systemic amyloidosis, acquired cutis laxa and cutaneous mucinosis in a patient with multiple myeloma*

A 57-year-old woman presented with periorbital ecchymoses, laxity in skin folds, polyneuropathy and bilateral carpal tunnel syndrome. A skin biopsy of the axillary lesion demonstrated fragmentation of elastic fibers, but with a negative von Kossa stain, consistent with cutis laxa. The diagnosis of primary systemic amyloidosis was made by the presence of amyloid material in the eyelid using hist...